SCHEMBL5453793

SCHEMBL5453793

CCCCCCCCCCCC(CCCCCC)c1cccc(C(=O)O)c1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
CYSLTR2 Q9NS75 1/20 0.49
CYSLTR1 Q9Y271 1/20 0.49
SLC37A4 O43826 1/20 0.46
KDM4E B2RXH2 2/20 0.44
HPGD P15428 1/20 0.44
HSD17B10 Q99714 1/20 0.44
PRSS1 P07477 1/20 0.42
PRSS2 P07478 1/20 0.42
PRSS3 P35030 1/20 0.42
KAT8 Q9H7Z6 4/20 0.41
BID P55957 3/20 0.41
MCL1 Q07820 3/20 0.41
BCL2L1 Q07817 2/20 0.41
BAK1 Q16611 2/20 0.41
PPARA Q07869 2/20 0.41
MEN1 O00255 1/20 0.41
RECQL P46063 1/20 0.41
KMT2A Q03164 1/20 0.41
PPARG P37231 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL368880 0.99 ALDH1A1 (0.49) ALDH1A1CYSLTR2CYSLTR1SLC37A4KDM4E
SCHEMBL9766367 0.94 ALDH1A1 (0.46) ALDH1A1CYSLTR2CYSLTR1SLC37A4KDM4E
SCHEMBL7792309 0.93 ALDH1A1 (0.45) ALDH1A1CYSLTR2CYSLTR1SLC37A4KDM4E
SCHEMBL7795743 0.93 ALDH1A1 (0.45) ALDH1A1CYSLTR2CYSLTR1SLC37A4KDM4E
SCHEMBL342806 0.93 ALDH1A1 (0.46) ALDH1A1CYSLTR2CYSLTR1SLC37A4KDM4E
SCHEMBL28349037 0.91 ALDH1A1 (0.44) ALDH1A1CYSLTR2CYSLTR1SLC37A4KDM4E
SCHEMBL9615354 0.87 ALDH1A1 (0.52) ALDH1A1SLC37A4KDM4EHPGDHSD17B10
SCHEMBL9504215 0.87 ALDH1A1 (0.52) ALDH1A1SLC37A4KDM4EHPGDHSD17B10
SCHEMBL9502958 0.87 ALDH1A1 (0.52) ALDH1A1SLC37A4KDM4EHPGDHSD17B10
SCHEMBL1769315 0.86 ALDH1A1 (0.57) ALDH1A1CYSLTR2CYSLTR1SLC37A4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2356972-B1 Method and kits for improving comfort of the intimate area JOHNSON & JOHNSON CONSUMER INC (US) 2016-04-20 EP claimed
EP-2356971-B1 Compositions for repelling fluid and uses thereof JOHNSON & JOHNSON CONSUMER INC (US) 2016-04-20 EP claimed
EP-1644053-B9 Skin friendly single-use product HARTMANN PAUL AG (DE) 2014-09-10 EP disclosed
EP-1644053-B1 Skin friendly single-use product HARTMANN PAUL AG (DE) 2014-06-18 EP disclosed
EP-2654665-A2 METHOD FOR DEVELOPING A LIQUID COMPOSITION TO BE APPLIED TO THE SKIN AS A FOAM AND A COMPOSITION THAT CAN BE APPLIED TOPICALLY MIKA Pharma Gesellschaft für die Entwicklung und Vermarktung pharmazeutischer Produkte mbH (DE) 2013-10-30 EP disclosed
WO-2012083906-A2 METHOD FOR DEVELOPING A LIQUID COMPOSITION TO BE APPLIED TO THE SKIN AS A FOAM AND A COMPOSITION THAT CAN BE APPLIED TOPICALLY MIKA PHARMA GESELLSCHAFT FÜR DIE ENTWICKLUNG UND VERMARKTUNG PHARMAZEUTISCHER PRODUKTE MBH (DE) 2012-06-28 WO disclosed
US-20070092462-A1 Cosmetic compositions CITICORP USA, INC. 2007-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070092462-A1 Cosmetic compositions PLOD3, COL14A1, COL2A1 ALDH1A1 2352/4885CYSLTR2 865/4885CYSLTR1 874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.