Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.30 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28231618 | 0.76 | DYRK1A (0.31) | DYRK1A | |
| SCHEMBL29618341 | 0.69 | DYRK1A (0.46) | DYRK1AALDH1A1MAPTKDM4ETP53 | |
| SCHEMBL126525 | 0.69 | DYRK1A (0.46) | DYRK1AALDH1A1MAPTKDM4ETP53 | |
| SCHEMBL23009509 | 0.69 | HSP90AA1 (0.41) | ALDH1A1MAPTKDM4EHSP90AA1POLB | |
| SCHEMBL30698015 | 0.68 | GRM5 (0.40) | ALDH1A1MAPT | |
| SCHEMBL30698038 | 0.68 | GRM5 (0.40) | ALDH1A1MAPT | |
| SCHEMBL13459980 | 0.68 | MAPT (0.36) | DYRK1AMAPTKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL9050761 | 0.68 | KDM4E (0.40) | DYRK1AALDH1A1MAPTKDM4EHSP90AA1 | |
| SCHEMBL9538581 | 0.67 | — | — | |
| SCHEMBL30749727 | 0.65 | ALDH1A1 (0.38) | ALDH1A1MAPTKDM4EHSP90AA1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192502-A1 | SPIROBICYCLIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2023-10-05 | — | — | WO | disclosed |
| US-H890-H | Herbicidal heterocyclicbenzylsulfonamides | Rorer, Morris P. (US) | 1991-02-05 | — | — | US | disclosed |