Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 7/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HTR3A | P46098 | 3/20 | 0.54 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.54 |
| ▸ | HTR3B | O95264 | 1/20 | 0.54 |
| ▸ | HTR5A | P47898 | 1/20 | 0.54 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.54 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8247499 | 0.84 | GAA (0.68) | HTR4GAAHTR3AHTR3EHTR3B | |
| SCHEMBL15650737 | 0.83 | HTR4 (0.83) | HTR4HTR3ACYP2D6CYP2C9 | |
| SCHEMBL10353676 | 0.78 | GAA (0.58) | HTR4GAAHTR3AHTR3EHTR3B | |
| SCHEMBL9766461 | 0.77 | HTR4 (0.65) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL10827995 | 0.76 | HTR4 (0.67) | HTR4HTR3A | |
| SCHEMBL10486813 | 0.76 | HTR4 (0.72) | HTR4HTR3ACYP2D6CYP2C9 | |
| SCHEMBL5319039 | 0.76 | HTR4 (0.67) | HTR4HTR3ACYP2D6CYP2C9 | |
| SCHEMBL7751850 | 0.76 | GAA (0.71) | HTR4GAAHTR3AHTR3EHTR3B | |
| SCHEMBL14817685 | 0.76 | GAA (0.71) | HTR4GAAHTR3AHTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL7301561 | 0.76 | GAA (0.56) | HTR4GAAHTR3AHTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2022257-A | — | — | None | — | — | JP | disclosed |
| US-5010108-A | Treatment of gastrointestinal disorders | POLI INDUSTRIA CHIMICA S.P.A. (IT) | 1991-04-23 | — | — | US | disclosed |
| JP-H0222257-A | N-CYCLOALKYLAMINOETHYLBENZAMIDE DERIVATIVE, ITS PRODUCTION AND PHARMACEUTICAL USE | POLI IND CHIM SPA | 1990-01-25 | — | — | JP | disclosed |
| EP-0333073-A2 | N-cycloalkylaminoethylbenzamide derivatives, their synthesis and pharmaceutical preparations | POLI INDUSTRIA CHIMICA S.p.A. (IT) | 1989-09-20 | — | — | EP | disclosed |