Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.47 |
| ▸ | SMO | Q99835 | 2/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | CTRC | Q99895 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17988099 | 0.81 | MEN1 (0.58) | MEN1KMT2AEHMT2ELANETSHR | |
| SCHEMBL20086223 | 0.76 | SMO (0.49) | MEN1KMT2AEHMT2SMOF2 | |
| SCHEMBL2025098 | 0.75 | MEN1 (0.58) | MEN1KMT2AEHMT2ALDH1A1MAPT | |
| SCHEMBL22767582 | 0.71 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1MAPTTSHR | |
| SCHEMBL13297796 | 0.70 | EHMT2 (0.49) | MEN1KMT2AEHMT2SMOF2 | |
| SCHEMBL28312625 | 0.70 | EHMT2 (0.41) | MEN1KMT2AEHMT2SMOGSK3A | |
| SCHEMBL8133525 | 0.70 | ELANE (0.61) | MEN1KMT2AGSK3AGSK3BMGLL | |
| SCHEMBL4076507 | 0.70 | EHMT2 (0.47) | MEN1KMT2AEHMT2SMOALDH1A1 | |
| SCHEMBL12899409 | 0.69 | EHMT2 (0.41) | MEN1KMT2AEHMT2SMOELANE | |
| SCHEMBL22661901 | 0.69 | EHMT2 (0.47) | MEN1KMT2AEHMT2SMOF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021587-A | Synthesis of N,3,4-trisubstituted-3-azoline-2-ones | PETROLITE CORPORATION (US) | 1991-06-04 | — | — | US | disclosed |