Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9875473 | 1.00 | RAB9A (0.38) | RAB9ASPHK1S1PR3CYP2C9HRH3 | |
| SCHEMBL9158838 | 0.97 | SPHK1 (0.40) | RAB9ASPHK1S1PR3CYP2C9HRH3 | |
| SCHEMBL9766712 | 0.97 | SPHK1 (0.40) | RAB9ASPHK1S1PR3CYP2C9HRH3 | |
| SCHEMBL9158847 | 0.97 | SPHK1 (0.40) | RAB9ASPHK1S1PR3CYP2C9HRH3 | |
| SCHEMBL9159174 | 0.95 | RAB9A (0.41) | RAB9ASPHK1CYP2C9HRH3MAPT | |
| SCHEMBL9159166 | 0.95 | RAB9A (0.41) | RAB9ASPHK1CYP2C9HRH3MAPT | |
| SCHEMBL9160931 | 0.91 | ACACB (0.38) | RAB9ACYP2C9HRH3LMNAMAPT | |
| SCHEMBL9160937 | 0.91 | ACACB (0.38) | RAB9ACYP2C9HRH3LMNAMAPT | |
| SCHEMBL9158454 | 0.86 | MAPT (0.38) | RAB9ACYP2C9LMNAMAPTL3MBTL1 | |
| SCHEMBL9158447 | 0.86 | MAPT (0.38) | RAB9ACYP2C9LMNAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991004248-A1 | PYRIDINE DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-04-04 | — | — | WO | disclosed |