Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 3/20 | 0.33 |
| ▸ | FNTB | P49356 | 3/20 | 0.33 |
| ▸ | CRYAB | P02511 | 2/20 | 0.33 |
| ▸ | CRYAA | P02489 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PRKCG | P05129 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9766742 | 1.00 | USP2 (0.40) | USP2ALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL9766780 | 0.92 | USP2 (0.38) | USP2ALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL9766776 | 0.92 | USP2 (0.38) | USP2ALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL9766810 | 0.88 | USP2 (0.39) | USP2ALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL9766802 | 0.88 | USP2 (0.39) | USP2ALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL9766770 | 0.85 | CRYAB (0.47) | USP2ALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL9766775 | 0.85 | CRYAB (0.47) | USP2ALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL9766769 | 0.81 | MAPT (0.48) | USP2ALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL9766774 | 0.81 | MAPT (0.48) | USP2ALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL9644062 | 0.80 | MAPT (0.45) | USP2ALDH1A1CYP3A4MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023250-A | Anticholesterol agents | SMITHKLINE BEECHAM CORPORATION (US) | 1991-06-11 | — | — | US | disclosed |