Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | CRYAB | P02511 | 5/20 | 0.40 |
| ▸ | CRYAA | P02489 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | EBP | Q15125 | 3/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9766769 | 1.00 | MAPT (0.48) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL9766806 | 0.87 | MAPT (0.49) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL9766812 | 0.87 | MAPT (0.49) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL9769622 | 0.85 | MAPT (0.47) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL9644062 | 0.84 | MAPT (0.45) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL9644065 | 0.84 | MAPT (0.45) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL9766870 | 0.83 | CRYAB (0.58) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL9766873 | 0.83 | CRYAB (0.58) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL9766748 | 0.81 | USP2 (0.40) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL9766742 | 0.81 | USP2 (0.40) | MAPTUSP2ALDH1A1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023250-A | Anticholesterol agents | SMITHKLINE BEECHAM CORPORATION (US) | 1991-06-11 | — | — | US | disclosed |