SCHEMBL9766757

CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(CC(=O)O)[C@@H]3C=C[C@H]4C(C)(C)CCC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 0.43

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	CDC25A	P30304	11/20	0.43

▸	EBP	Q15125	5/20	0.39

▸	CDC25B	P30305	6/20	0.39

▸	FNTA	P49354	3/20	0.36

▸	FNTB	P49356	3/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9766760	1.00	CDC25A (0.43)	CDC25AEBPCDC25BFNTAFNTB
SCHEMBL9766820	0.86	HMGCR (0.46)	CDC25AEBPFNTAFNTB
SCHEMBL9766722	0.86	HMGCR (0.46)	CDC25AEBPFNTAFNTB
SCHEMBL9766832	0.81	NPC1L1 (0.44)	EBP
SCHEMBL9766753	0.72	HMGCR (0.49)	CDC25AEBPCDC25BFNTAFNTB
SCHEMBL9766747	0.72	HMGCR (0.49)	CDC25AEBPCDC25BFNTAFNTB
SCHEMBL14034589	0.71	CDC25A (0.54)	CDC25AEBPCDC25B
SCHEMBL14116734	0.71	CDC25A (0.54)	CDC25AEBPCDC25B
SCHEMBL9766739	0.70	GPBAR1 (0.53)	CDC25A
SCHEMBL9766744	0.70	GPBAR1 (0.53)	CDC25A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5023250-A	Anticholesterol agents	SMITHKLINE BEECHAM CORPORATION (US)	1991-06-11	—	—	US	disclosed