Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 9/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9326325 | 0.75 | MEN1 (0.48) | MEN1KMT2ABRAFKDRRAF1 | |
| SCHEMBL21572243 | 0.75 | GCK (0.42) | P2RY1KDM4EMEN1CYP1A2CYP2C19 | |
| SCHEMBL9327661 | 0.71 | MEN1 (0.54) | MEN1CYP1A2KMT2ABRAFKDR | |
| SCHEMBL1881939 | 0.71 | KDR (0.69) | METKDRKITPDGFRA | |
| SCHEMBL10968995 | 0.70 | KMT2A (0.69) | P2RY1METKDM4EMEN1CYP1A2 | |
| SCHEMBL9767364 | 0.70 | MEN1 (0.45) | P2RY1MAPK14METRAB9AKDM4E | |
| SCHEMBL19888724 | 0.70 | KDR (0.49) | MAPK14RAB9AKDRFLT1NPC1 | |
| SCHEMBL19888723 | 0.69 | ABL1 (0.59) | MAPK14METBRAFKDRRIPK2 | |
| SCHEMBL8618906 | 0.69 | GCGR (0.56) | MEN1KMT2ABRAFKDR | |
| SCHEMBL23352868 | 0.69 | RAB9A (0.70) | RAB9AMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3002164-A | — | — | None | — | — | JP | disclosed |
| JP-H032164-A | BENZOYLPHENYLUREA | CIBA GEIGY AG | 1991-01-08 | — | — | JP | disclosed |
| EP-0397601-A1 | Benzoylphenylureas | CIBA-GEIGY AG (CH) | 1990-11-14 | — | — | EP | disclosed |