Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.30 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9767154 | 0.68 | ALDH2 (0.31) | GPR84CA2 | |
| SCHEMBL9766905 | 0.64 | GPR84 (0.31) | GPR84 | |
| SCHEMBL14576645 | 0.63 | MAOB (0.53) | — | |
| SCHEMBL7902957 | 0.61 | CA2 (0.52) | GPR84CA2 | |
| SCHEMBL29273648 | 0.61 | LMNA (0.50) | GPR84CA2 | |
| SCHEMBL7902271 | 0.61 | CA2 (0.52) | GPR84CA2 | |
| SCHEMBL2915731 | 0.61 | CA2 (0.52) | GPR84CA2 | |
| SCHEMBL28541213 | 0.61 | LMNA (0.50) | GPR84CA2 | |
| SCHEMBL13013753 | 0.61 | LMNA (0.50) | GPR84CA2 | |
| SCHEMBL13938058 | 0.60 | LMNA (0.54) | GPR84CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5013850-A | 4-ethyl and 4-ethenyl-5-hydroxy-2(5H)-furanones substituted on alpha carbon of the ethyl or ethenyl side chain with a long chain alkyl group and on the beta carbon with a polar group, as anti-inflammatory agents | ALLERGAN, INC. (US) | 1991-05-07 | — | — | US | disclosed |