Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 12/20 | 0.67 |
| ▸ | CES1 | P23141 | 10/20 | 0.67 |
| ▸ | CES2 | O00748 | 6/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8115343 | 0.91 | FAAH (0.56) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL20654764 | 0.85 | CES2 (0.59) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL10966855 | 0.80 | FAAH (1.00) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL439276 | 0.80 | CES2 (0.52) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL9192692 | 0.80 | FAAH (1.00) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL31152148 | 0.80 | FAAH (1.00) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL4653611 | 0.80 | FAAH (1.00) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL2819894 | 0.80 | FAAH (1.00) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL28471077 | 0.80 | FAAH (1.00) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL8515257 | 0.80 | FAAH (1.00) | FAAHCES1CES2MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5057626-A | Difluoroketones from difluoroacylsilanes | PFIZER INC. (US) | 1991-10-15 | — | — | US | disclosed |
| US-4996345-A | Difluoroketones from difluoroacylsilanes | PFIZER INC. (US) | 1991-02-26 | — | — | US | disclosed |