Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 13/20 | 0.56 |
| ▸ | CES1 | P23141 | 9/20 | 0.54 |
| ▸ | CES2 | O00748 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | PLA2G4C | Q9UP65 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9767600 | 0.91 | FAAH (0.67) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL20654764 | 0.84 | CES2 (0.59) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL439276 | 0.84 | CES2 (0.52) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL809819 | 0.78 | FAAH (0.86) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL18965607 | 0.78 | CYP1A2 (0.46) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL18965382 | 0.77 | CES2 (0.46) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL15744200 | 0.77 | CES2 (0.46) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL23776682 | 0.76 | FAAH (0.43) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL1706449 | 0.76 | CES2 (0.54) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL12396593 | 0.76 | CES2 (0.54) | FAAHCES1CES2MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997459-A1 | Intermediates for preparing retroviral protease inhibiting compounds | Abbott Laboratories (US) | 2000-05-03 | — | — | EP | disclosed |