Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 3/20 | 0.43 |
| ▸ | MMP3 | P08254 | 3/20 | 0.43 |
| ▸ | PTGES | O14684 | 3/20 | 0.43 |
| ▸ | MMP8 | P22894 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP7 | P09237 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9767669 | 0.99 | LMNA (0.43) | LMNASIGMAR1MMP1MMP3PTGES | |
| SCHEMBL9767585 | 0.76 | GPR88 (0.51) | LMNAMMP1MMP3PTGESMEN1 | |
| SCHEMBL6998369 | 0.73 | LMNA (0.53) | LMNAPTGESMEN1KMT2AALDH1A1 | |
| SCHEMBL7996489 | 0.71 | LMNA (0.51) | LMNASIGMAR1PTGESMEN1KMT2A | |
| SCHEMBL7534139 | 0.70 | LMNA (0.50) | LMNAPTGESMEN1KMT2AALDH1A1 | |
| SCHEMBL574486 | 0.69 | LMNA (0.61) | LMNAMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL1195514 | 0.69 | LMNA (0.78) | LMNAMEN1KMT2AALDH1A1NPSR1 | |
| Hydrochloric Acid SCHEMBL18342101 | 0.68 | LMNA (0.51) | LMNAMEN1KMT2AALDH1A1NPSR1 | |
| Hydrochloric Acid SCHEMBL18342320 | 0.68 | LMNA (0.51) | LMNAMEN1KMT2AALDH1A1NPSR1 | |
| Hydrochloric Acid SCHEMBL18342102 | 0.68 | LMNA (0.51) | LMNAMEN1KMT2AALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019647-A | Antigrowth and anticarconogenic hexapeptide | MERCK & CO., INC. (US) | 1991-05-28 | — | — | US | disclosed |