SCHEMBL574486

SCHEMBL574486

CCCN(Cc1ccccc1)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.61
HDAC1 Q13547 1/20 0.56
HDAC6 Q9UBN7 1/20 0.56
PKM P14618 1/20 0.56
ALDH1A1 P00352 4/20 0.55
TP53 P04637 1/20 0.55
LIMK1 P53667 1/20 0.54
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
TSHR P16473 1/20 0.51
MAPK1 P28482 1/20 0.51
NPSR1 Q6W5P4 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3662061 0.89 LMNA (0.58) LMNAHDAC1HDAC6PKMALDH1A1
SCHEMBL1753870 0.89 HDAC6 (0.58) LMNAHDAC1HDAC6PKMLIMK1
SCHEMBL3920435 0.87 LMNA (0.56) LMNAHDAC1HDAC6PKMALDH1A1
SCHEMBL1926269 0.87 HDAC1 (0.73) LMNAHDAC1HDAC6PKMALDH1A1
SCHEMBL8773510 0.85 CNR2 (0.64) LMNAHDAC1HDAC6PKMLIMK1
SCHEMBL2721394 0.85 REN (0.69) LMNAHDAC1HDAC6PKMALDH1A1
SCHEMBL15546987 0.85 CNR2 (0.64) LMNAHDAC1HDAC6PKMLIMK1
SCHEMBL4352375 0.85 HDAC1 (0.50) LMNAHDAC1HDAC6PKMALDH1A1
SCHEMBL13731746 0.84 LMNA (0.53) LMNAHDAC1HDAC6PKMALDH1A1
SCHEMBL13911255 0.84 HDAC1 (0.54) LMNAHDAC1HDAC6PKMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2739670-B1 SOL-GEL DERIVED COMPOSITIONS ABS MAT INC (US) 2023-10-11 EP disclosed
US-10934504-B2 Laundry treatment compositions comprising perfume and silica microparticles CONOPCO, INC. (US) 2021-03-02 US disclosed
US-10881598-B2 Method of using personal and home care compositions containing a sol-gel derived material ABS MATERIALS, INC. (US) 2021-01-05 US disclosed
EP-3535359-B1 LAUNDRY TREATMENT COMPOSITIONS COMPRISING PERFUME AND SILICA MICROPARTICLES UNILEVER PLC (GB) 2020-05-13 EP disclosed
US-20200056125-A1 LAUNDRY TREATMENT COMPOSITIONS COMPRISING PERFUME AND SILICA MICROPARTICLES CONOPCO, INC., D/B/A UNILEVER (US) 2020-02-20 US disclosed
EP-3568440-A1 SWELLABLE SILICA MICROPARTICLES Unilever PLC (GB) 2019-11-20 EP disclosed
US-20190330571-A1 SWELLABLE SILICA MICROPARTICLE CONOPCO, INC., D/B/A UNILEVER (US) 2019-10-31 US disclosed
US-20190290552-A1 ETHANOLIC COMPOSITIONS COMPRISING PERFUME CONOPCO, INC., D/B/A UNILEVER (US) 2019-09-26 US disclosed
EP-3535030-A1 ETHANOLIC COMPOSITIONS COMPRISING PERFUME Unilever PLC (GB) 2019-09-11 EP disclosed
EP-3535359-A1 LAUNDRY TREATMENT COMPOSITIONS COMPRISING PERFUME AND SILICA MICROPARTICLES Unilever PLC (GB) 2019-09-11 EP disclosed
EP-2739670-A1 SOL-GEL DERIVED COMPOSITIONS ABS Materials, Inc. (US) 2014-06-11 EP disclosed
US-20130292620-A1 METHOD AND SYSTEM FOR APPLYING FORCE AGAINST A SOLID OBJECT USING A SWELLABLE SOL-GEL DERIVED MATERIAL ABS MATERIALS, INC. (US) 2013-11-07 US disclosed
EP-2601127-A1 METHOD AND SYSTEM FOR APPLYING FORCE AGAINST A SOLID OBJECT USING A SWELLABLE SOL-GEL DERIVED MATERIAL ABS Materials, Inc. (US) 2013-06-12 EP disclosed
WO-2013022962-A1 METHOD FOR REMOVING IONIC SPECIES CONTAINED IN AN AQUEOUS PHASE USING A SOL GEL-DERIVED COMPOSITE MATERIAL ABS MATERIALS, INC. (US) 2013-02-14 WO disclosed
WO-2013019965-A1 SOL-GEL DERIVED COMPOSITIONS ABS MATERIALS, INC. (US) 2013-02-07 WO disclosed
US-20130026093-A1 METHOD FOR REMOVING IONIC SPECIES CONTAINED IN AN AQUEOUS PHASE USING A SOL GEL-DERIVED COMPOSITE MATERIAL ABS MATERIALS, INC. (US) 2013-01-31 US disclosed
US-20130029843-A1 SOL-GEL DERIVED COMPOSITIONS ABS MATERIALS, INC. (US) 2013-01-31 US disclosed
WO-2012019033-A1 METHOD AND SYSTEM FOR APPLYING FORCE AGAINST A SOLID OBJECT USING A SWELLABLE SOL-GEL DERIVED MATERIAL ABS MATERIALS, INC. (US) 2012-02-09 WO disclosed
EP-1678158-A1 PROCESS FOR THE PREPARATION OF GLYCERALDEHYDE ACETONIDE DSM IP Assets B.V. (NL) 2006-07-12 EP disclosed
WO-2005040149-A1 PROCESS FOR THE PREPARATION OF GLYCERALDEHYDE ACETONIDE DSM IP ASSETS B.V. (NL) 2005-05-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10881598-B2 Method of using personal and home care compositions containing a sol-gel derived material FPR3, FPR1, MSN LMNA 1556/4885HDAC1 1171/4885HDAC6 2597/4885
US-20190290552-A1 ETHANOLIC COMPOSITIONS COMPRISING PERFUME EXOSC5, EXOSC4, EXOSC9 LMNA 1161/4885HDAC1 3178/4885HDAC6 4250/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.