Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.70 |
| ▸ | RAB9A | P51151 | 4/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.64 |
| ▸ | NT5E | P21589 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.58 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.58 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.58 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.58 |
| ▸ | NAMPT | P43490 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8420420 | 0.90 | NPC1 (0.69) | NPC1RAB9ASMN1; SMN2KMT2AMAPT | |
| SCHEMBL611657 | 0.90 | NPC1 (0.76) | NPC1RAB9ASMN1; SMN2KMT2ANT5E | |
| SCHEMBL9767723 | 0.90 | NPC1 (0.76) | NPC1RAB9ASMN1; SMN2KMT2ANT5E | |
| SCHEMBL10939703 | 0.90 | NPC1 (0.76) | NPC1RAB9ASMN1; SMN2KMT2ANT5E | |
| SCHEMBL17013406 | 0.90 | NPC1 (0.69) | NPC1RAB9ASMN1; SMN2KMT2AMAPT | |
| SCHEMBL16589425 | 0.85 | MAPT (0.77) | NPC1RAB9ASMN1; SMN2KMT2ANT5E | |
| SCHEMBL10192061 | 0.85 | RAB9A (0.81) | NPC1RAB9ASMN1; SMN2KMT2ANT5E | |
| SCHEMBL493839 | 0.85 | RAB9A (0.81) | NPC1RAB9ASMN1; SMN2KMT2ANT5E | |
| SCHEMBL6710662 | 0.83 | MITF (0.68) | NPC1RAB9ASMN1; SMN2KMT2ANT5E | |
| SCHEMBL2409003 | 0.83 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2KMT2ANT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3398970-B1 | A METHOD OF SYNTHESIZING CELLULOSE CARBONATE | AGENCY SCIENCE TECH & RES (SG) | 2020-02-12 | — | — | EP | disclosed |