Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | NMT1 | P30419 | 4/20 | 0.37 |
| ▸ | NMT2 | O60551 | 3/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6431308 | 0.81 | SIGMAR1 (0.54) | SIGMAR1METAP1CYP1A2EPHX1 | |
| SCHEMBL9596846 | 0.77 | SIGMAR1 (0.61) | SIGMAR1METAP1CYP1A2 | |
| SCHEMBL28893954 | 0.77 | SIGMAR1 (0.61) | SIGMAR1METAP1CYP1A2 | |
| SCHEMBL8014520 | 0.76 | SIGMAR1 (0.48) | SIGMAR1METAP1CYP1A2EPHX1 | |
| SCHEMBL24324140 | 0.76 | DPP4 (0.41) | METAP1 | |
| SCHEMBL24323692 | 0.76 | — | — | |
| SCHEMBL24323716 | 0.76 | DPP4 (0.41) | METAP1 | |
| SCHEMBL11462647 | 0.76 | SIGMAR1 (0.50) | SIGMAR1METAP1CYP1A2NMT1NMT2 | |
| SCHEMBL101244 | 0.76 | SIGMAR1 (0.45) | SIGMAR1METAP1CYP1A2NMT1NMT2 | |
| SCHEMBL24684376 | 0.76 | CYP1A2 (0.59) | SIGMAR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990666-A | Contacting with Raney cobalt; heating, pressurization | W. R. GRACE & CO.-CONN. (US) | 1991-02-05 | — | — | US | disclosed |