Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 2/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GAPDH | P04406 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9767800 | 0.85 | ALDH1A1 (0.67) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL9768093 | 0.82 | ALDH1A1 (0.67) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL9767841 | 0.80 | SMN1; SMN2 (0.68) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL9767850 | 0.77 | RAB9A (0.56) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL9767935 | 0.76 | SMN1; SMN2 (0.62) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL9767945 | 0.75 | SMN1; SMN2 (0.55) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL13854028 | 0.74 | RAB9A (0.69) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL9767854 | 0.74 | RAB9A (0.69) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL9768217 | 0.73 | RAB9A (0.67) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| Potassium Ion SCHEMBL9767821 | 0.72 | RAB9A (0.66) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006548-A | Hyaluronidase inhibitors, antiallergens, immunomodulators | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-04-09 | — | — | US | disclosed |
| EP-0153850-B1 | ACRYLAMIDOBENZOIC ACID DERIVATIVES AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-09-13 | — | — | EP | disclosed |
| EP-0153850-A1 | Acrylamidobenzoic acid derivatives and their use | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1985-09-04 | — | — | EP | disclosed |