Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.67 |
| ▸ | NPC1 | O15118 | 7/20 | 0.67 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.58 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.58 |
| ▸ | TRPA1 | O75762 | 7/20 | 0.56 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9767854 | 0.99 | RAB9A (0.69) | RAB9ASMN1; SMN2NPC1TRPM2LTB4R | |
| SCHEMBL13854028 | 0.99 | RAB9A (0.69) | RAB9ASMN1; SMN2NPC1TRPM2LTB4R | |
| Potassium Ion SCHEMBL9767821 | 0.85 | RAB9A (0.66) | RAB9ASMN1; SMN2NPC1KMT2AMAPT | |
| SCHEMBL9767835 | 0.85 | RAB9A (0.66) | RAB9ASMN1; SMN2NPC1KMT2AMAPT | |
| SCHEMBL9768214 | 0.85 | RAB9A (0.66) | RAB9ASMN1; SMN2NPC1KMT2AMAPT | |
| SCHEMBL9767841 | 0.84 | SMN1; SMN2 (0.68) | RAB9ASMN1; SMN2NPC1KMT2AMAPT | |
| SCHEMBL5147438 | 0.84 | RAB9A (0.57) | RAB9ASMN1; SMN2NPC1TRPM2LTB4R | |
| SCHEMBL5147433 | 0.84 | RAB9A (0.57) | RAB9ASMN1; SMN2NPC1TRPM2LTB4R | |
| Lysine SCHEMBL9768070 | 0.82 | RAB9A (0.50) | RAB9ASMN1; SMN2NPC1TRPM2LTB4R | |
| SCHEMBL2273164 | 0.81 | RAB9A (0.54) | RAB9ASMN1; SMN2NPC1TRPA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006548-A | Hyaluronidase inhibitors, antiallergens, immunomodulators | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-04-09 | — | — | US | disclosed |
| EP-0153850-B1 | ACRYLAMIDOBENZOIC ACID DERIVATIVES AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-09-13 | — | — | EP | disclosed |
| EP-0153850-A1 | Acrylamidobenzoic acid derivatives and their use | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1985-09-04 | — | — | EP | disclosed |