Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.42 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.42 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16796683 | 0.83 | NPC1 (0.46) | NPC1RAB9ALMNACTSKMEN1 | |
| SCHEMBL3606752 | 0.75 | LMNA (0.44) | NPC1RAB9ALMNAMEN1KMT2A | |
| SCHEMBL3606756 | 0.75 | LMNA (0.44) | NPC1RAB9ALMNAMEN1KMT2A | |
| SCHEMBL17101270 | 0.74 | LMNA (0.46) | LMNAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL10584191 | 0.74 | ALDH1A1 (0.49) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11566872 | 0.74 | RAB9A (0.46) | NPC1RAB9ACTSKALDH1A1KCNJ6 | |
| SCHEMBL9208767 | 0.74 | RAB9A (0.46) | NPC1RAB9ALMNACTSKSMN1; SMN2 | |
| SCHEMBL11346948 | 0.73 | KMT2A (0.38) | NPC1RAB9ALMNACTSKMEN1 | |
| SCHEMBL10529570 | 0.73 | NPC1 (0.46) | NPC1RAB9ALMNAMEN1KMT2A | |
| SCHEMBL28385947 | 0.73 | RAB9A (0.40) | NPC1RAB9ALMNACTSKMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5013354-A | Tetrahydrophthalimido group, herbicides | BASF AKTIENGESELLSCHAFT (DE) | 1991-05-07 | — | — | US | disclosed |
| EP-0300398-A2 | 3-Phenylpropionic acid derivatives | BASF Aktiengesellschaft (DE) | 1989-01-25 | — | — | EP | disclosed |