Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | HNF4A | P41235 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22310170 | 0.89 | HDAC4 (0.50) | HPGDALDH1A1HSD17B10BCL2L1HDAC4 | |
| SCHEMBL10338434 | 0.88 | HDAC4 (0.53) | HPGDALDH1A1HSD17B10BCL2L1HDAC4 | |
| SCHEMBL8778337 | 0.88 | HDAC4 (0.53) | HPGDALDH1A1HSD17B10BCL2L1HDAC4 | |
| SCHEMBL8778334 | 0.88 | HPGD (0.70) | HPGDALDH1A1HSD17B10BCL2L1HDAC4 | |
| SCHEMBL8914805 | 0.88 | HPGD (0.70) | HPGDALDH1A1HSD17B10BCL2L1HDAC4 | |
| SCHEMBL30127606 | 0.88 | HPGD (0.70) | HPGDALDH1A1HSD17B10BCL2L1HDAC4 | |
| Bicarbonate SCHEMBL9704219 | 0.83 | HDAC4 (0.53) | HPGDALDH1A1HSD17B10BCL2L1HDAC4 | |
| SCHEMBL13368747 | 0.82 | HPGD (0.60) | HPGDALDH1A1HSD17B10BCL2L1HDAC4 | |
| SCHEMBL1639143 | 0.81 | HSD17B1 (0.43) | HDAC4HDAC2HDAC8ALOX5BACE1 | |
| SCHEMBL10227395 | 0.81 | PTGER1 (0.41) | HDAC4HDAC2HDAC8ALOX5BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5013815-A | Aromatic polyether sulfones, a process for their production and their use | BAYER AKTIENGESELLSCHAFT (DE) | 1991-05-07 | — | — | US | disclosed |