Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | AGER | Q15109 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22187005 | 0.83 | ALDH1A1 (0.54) | HTTNPSR1KDM4EL3MBTL1TDP1 | |
| SCHEMBL6648818 | 0.78 | HTT (0.43) | HTTNPSR1KDM4EL3MBTL1TDP1 | |
| SCHEMBL28358580 | 0.77 | ALDH1A1 (0.46) | KDM4ETDP1ALDH1A1MAPTPOLB | |
| SCHEMBL174073 | 0.74 | KMT2A (0.49) | HTTNPSR1KDM4EL3MBTL1TDP1 | |
| SCHEMBL9768097 | 0.72 | KDM4E (0.48) | KDM4EL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL27544152 | 0.71 | KDM4E (0.56) | KDM4ETDP1ALDH1A1MAPTPOLB | |
| SCHEMBL31562044 | 0.71 | KDM4E (0.56) | KDM4ETDP1ALDH1A1MAPTPOLB | |
| SCHEMBL5641708 | 0.71 | LIPE (0.43) | HTTNPSR1KDM4EL3MBTL1TDP1 | |
| SCHEMBL28996726 | 0.71 | TSHR (0.42) | HTTNPSR1KDM4EL3MBTL1TDP1 | |
| SCHEMBL935444 | 0.69 | HTT (0.54) | HTTNPSR1KDM4EL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006548-A | Hyaluronidase inhibitors, antiallergens, immunomodulators | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-04-09 | — | — | US | disclosed |
| EP-0153850-B1 | ACRYLAMIDOBENZOIC ACID DERIVATIVES AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-09-13 | — | — | EP | disclosed |