Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 2/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2600032 | 0.80 | NR3C1 (0.42) | NR3C1PGRNR3C2SMN1; SMN2ALDH1A1 | |
| SCHEMBL564833 | 0.80 | NR3C1 (0.40) | NR3C1PGRNR3C2SMN1; SMN2ALDH1A1 | |
| SCHEMBL564609 | 0.77 | NPC1 (0.43) | NR3C1PGRNR3C2SMN1; SMN2ALDH1A1 | |
| SCHEMBL564445 | 0.77 | NR3C1 (0.46) | NR3C1PGRNR3C2SMN1; SMN2ALDH1A1 | |
| SCHEMBL15667983 | 0.77 | NR3C1 (0.36) | NR3C1PGRNR3C2ALDH1A1CYP1A2 | |
| SCHEMBL25039130 | 0.76 | P2RX7 (0.40) | NR3C1PGRNR3C2SMN1; SMN2ALDH1A1 | |
| SCHEMBL257076 | 0.74 | P2RX7 (0.48) | SMN1; SMN2ALDH1A1LMNAP2RX7CYP1A2 | |
| SCHEMBL2559866 | 0.73 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1HTTLMNAP2RX7 | |
| SCHEMBL30515582 | 0.73 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1HTTLMNAP2RX7 | |
| SCHEMBL25039129 | 0.71 | NR3C1 (0.42) | NR3C1PGRNR3C2SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5013354-A | Tetrahydrophthalimido group, herbicides | BASF AKTIENGESELLSCHAFT (DE) | 1991-05-07 | — | — | US | disclosed |
| EP-0300398-A2 | 3-Phenylpropionic acid derivatives | BASF Aktiengesellschaft (DE) | 1989-01-25 | — | — | EP | disclosed |