Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 4/20 | 0.48 |
| ▸ | ALPG | P10696 | 4/20 | 0.48 |
| ▸ | TOP1 | P11387 | 1/20 | 0.48 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9768023 | 0.84 | ALPL (0.51) | ALPLALPGTOP1PLAAMMP1 | |
| SCHEMBL9768260 | 0.83 | ERCC1 (0.60) | AKR1C3ALPLALPGTOP1PLAA | |
| SCHEMBL9768241 | 0.83 | AKR1C3 (0.49) | AKR1C3ALPLALPGTOP1PLAA | |
| SCHEMBL9768047 | 0.83 | CA12 (0.55) | AKR1C3ALPLALPGTOP1PLAA | |
| SCHEMBL9768088 | 0.83 | AKR1C3 (0.49) | AKR1C3ALPLALPGTOP1PLAA | |
| SCHEMBL9768234 | 0.77 | INSR (0.57) | AKR1C3ALPLALPGPLAAMEN1 | |
| SCHEMBL9768152 | 0.75 | ALPL (0.51) | ALPLALPGTOP1PLAAMMP1 | |
| SCHEMBL1430415 | 0.75 | MEN1 (0.58) | AKR1C3MMP1MMP2MMP9MEN1 | |
| SCHEMBL9768107 | 0.75 | ALPL (0.51) | ALPLALPGTOP1PLAAMMP1 | |
| SCHEMBL9768193 | 0.75 | CA12 (0.61) | ALPLALPGTOP1PLAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5047592-A | Selective hydrogenolysis process | ETHYL CORPORATION (US) | 1991-09-10 | — | — | US | disclosed |