SCHEMBL5147433

SCHEMBL5147433

O=C(/C=C/c1cccs1)Nc1cc(-c2ccccc2)ccc1C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 7/20 0.57
SMN1; SMN2 Q16637 7/20 0.57
NPC1 O15118 6/20 0.57
KMT2A Q03164 5/20 0.56
ALDH1A1 P00352 5/20 0.56
MAPT P10636 4/20 0.56
KDM4E B2RXH2 4/20 0.56
UBE2I P63279 2/20 0.56
SAE1 Q9UBE0 2/20 0.56
UBA2 Q9UBT2 2/20 0.56
POLB P06746 1/20 0.56
PKM P14618 1/20 0.56
BLM P54132 1/20 0.56
HKDC1 Q2TB90 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
TRPM2 O94759 5/20 0.55
LTB4R Q15722 1/20 0.55
MEN1 O00255 4/20 0.54
HTT P42858 3/20 0.54
LMNA P02545 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5147438 1.00 RAB9A (0.57) RAB9ASMN1; SMN2NPC1KMT2AALDH1A1
SCHEMBL13854028 0.85 RAB9A (0.69) RAB9ASMN1; SMN2NPC1KMT2AALDH1A1
SCHEMBL9767854 0.85 RAB9A (0.69) RAB9ASMN1; SMN2NPC1KMT2AALDH1A1
SCHEMBL9768217 0.84 RAB9A (0.67) RAB9ASMN1; SMN2NPC1KMT2AALDH1A1
SCHEMBL2273164 0.83 RAB9A (0.54) RAB9ASMN1; SMN2NPC1KMT2AALDH1A1
SCHEMBL2273169 0.83 RAB9A (0.54) RAB9ASMN1; SMN2NPC1KMT2AALDH1A1
SCHEMBL2269338 0.82 TRPM2 (0.75) RAB9ASMN1; SMN2NPC1KMT2AMAPT
SCHEMBL2269335 0.82 TRPM2 (0.75) RAB9ASMN1; SMN2NPC1KMT2AMAPT
SCHEMBL2274104 0.78 TRPM2 (0.76) RAB9ASMN1; SMN2NPC1KMT2AMAPT
SCHEMBL2274109 0.78 TRPM2 (0.76) RAB9ASMN1; SMN2NPC1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101094829-B novel anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO.,LTD. (JP) 2012-02-08 CN disclosed
CN-101094829-A Novel anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO LTD (JP) 2007-12-26 CN disclosed
EP-1820795-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2007-08-22 EP disclosed