Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 4/20 | 0.38 |
| ▸ | CACNG8 | Q8WXS5 | 4/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7428387 | 0.81 | MAPT (0.45) | MAPTALDH1A1KDM4EGAAGRIA1 | |
| SCHEMBL29910923 | 0.78 | MAPT (0.58) | MAPTALDH1A1KDM4EGAAGRIA1 | |
| SCHEMBL4569783 | 0.78 | MAPT (0.58) | MAPTALDH1A1KDM4EGAAGRIA1 | |
| SCHEMBL265030 | 0.75 | MAPT (0.48) | MAPTALDH1A1KDM4EGAAGRIA1 | |
| SCHEMBL4136607 | 0.75 | PTGS2 (0.55) | MAPTALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL265008 | 0.74 | GAA (0.49) | MAPTALDH1A1KDM4EGAAGRIA1 | |
| SCHEMBL13969591 | 0.72 | ALDH1A1 (0.48) | MAPTALDH1A1GAAPKMRAB9A | |
| SCHEMBL19880496 | 0.72 | MAPT (0.46) | MAPTALDH1A1KDM4EGAAGRIA1 | |
| SCHEMBL18500486 | 0.70 | PKM (0.44) | MAPTALDH1A1KDM4EGAAGRIA1 | |
| SCHEMBL9768297 | 0.70 | MAPT (0.43) | MAPTALDH1A1KDM4EGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5034401-A | Cardiovascular disorders or antiischemia agents | SYNTHELABO (FR) | 1991-07-23 | — | — | US | disclosed |