Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917380 | 0.91 | ALDH1A1 (0.45) | PRMT5ALDH1A1LMNAROCK2ROCK1 | |
| SCHEMBL8910713 | 0.84 | ADRB3 (0.52) | POLBADRB3SMN1; SMN2LMNA | |
| SCHEMBL8366885 | 0.81 | OPRM1 (0.51) | — | |
| SCHEMBL8911567 | 0.80 | ADRB3 (0.55) | ADRB3 | |
| SCHEMBL8910176 | 0.77 | TDP1 (0.53) | POLBLMNAROCK2ROCK1 | |
| SCHEMBL7036804 | 0.76 | ADRB3 (0.77) | ADRB3 | |
| SCHEMBL7036235 | 0.76 | ADRB3 (0.77) | ADRB3 | |
| SCHEMBL3705016 | 0.74 | ADRB3 (0.54) | ADRB3ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7930108 | 0.74 | KMT2A (0.57) | POLBLMNAROCK2ROCK1 | |
| SCHEMBL11949257 | 0.73 | SMN1; SMN2 (0.65) | PRMT5POLBALDH1A1SMN1; SMN2CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5077406-A | Cyclization, deprotecting and salt formation | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-12-31 | — | — | US | disclosed |