Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 5/20 | 0.50 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.50 |
| ▸ | MAOA | P21397 | 4/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.49 |
| ▸ | GSK3A | P49840 | 2/20 | 0.49 |
| ▸ | GSK3B | P49841 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.49 |
| ▸ | MGAM | O43451 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3888726 | 0.90 | CDK5 (0.61) | CDK5CDK5R1MAOADYRK1AGSK3A | |
| SCHEMBL9781515 | 0.89 | CDK5 (0.64) | CDK5CDK5R1MAOADYRK1AGSK3A | |
| SCHEMBL10664986 | 0.89 | CDK5 (0.52) | CDK5CDK5R1MAOADYRK1AGSK3A | |
| SCHEMBL31506760 | 0.89 | CDK5 (0.52) | CDK5CDK5R1MAOADYRK1AGSK3A | |
| SCHEMBL9768431 | 0.84 | MAP3K11 (0.49) | MAOAKDM4EMEN1HPGDKMT2A | |
| SCHEMBL9781510 | 0.82 | MAOA (0.51) | CDK5CDK5R1MAOADYRK1AGSK3A | |
| SCHEMBL9781435 | 0.81 | ESR2 (0.56) | CDK5CDK5R1MAOADYRK1AGSK3A | |
| SCHEMBL9781428 | 0.80 | CDK5 (0.62) | CDK5CDK5R1MAOADYRK1AGSK3A | |
| SCHEMBL148273 | 0.80 | LMNA (0.49) | CDK5CDK5R1MAOADYRK1AGSK3A | |
| SCHEMBL31506767 | 0.80 | MAPT (0.50) | KDM4EMEN1HPGDKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2142793-A | — | — | None | — | — | JP | disclosed |
| JP-2142792-A | — | — | None | — | — | JP | disclosed |
| JP-63297325-A | — | — | None | — | — | JP | disclosed |
| US-5073553-A | Treatment or prevention of osteoporosis | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1991-12-17 | — | — | US | disclosed |
| US-5023261-A | Inhibits bone resorption, stimulates bone hardening and growth | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1991-06-11 | — | — | US | disclosed |
| JP-H02142792-A | NOVEL BENZOFUROQUINOLINE DERIVATIVE | KISSEI PHARMACEUT CO LTD | 1990-05-31 | — | — | JP | disclosed |
| JP-H02142793-A | NOVEL BENZOFUROQUINOLINE DERIVATIVE | KISSEI PHARMACEUT CO LTD | 1990-05-31 | — | — | JP | disclosed |
| EP-0370760-A2 | Benzofuro[3,2-c]quinoline compounds | Kissei Pharmaceutical Co., Ltd. (JP) | 1990-05-30 | — | — | EP | disclosed |
| EP-0357172-A2 | Benzofuro[3,2-c]Quinoline compounds | Kissei Pharmaceutical Co., Ltd. (JP) | 1990-03-07 | — | — | EP | disclosed |
| JP-S63297325-A | REMEDY FOR OSTEOPOROSIS | KISSEI PHARMACEUT CO LTD | 1988-12-05 | — | — | JP | disclosed |
| EP-0293146-A1 | Benzofuro [3,2-c] quinoline compounds | Kissei Pharmaceutical Co. Ltd. (JP) | 1988-11-30 | — | — | EP | disclosed |