Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K11 | Q16584 | 2/20 | 0.49 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PARP1 | P09874 | 2/20 | 0.48 |
| ▸ | TNKS | O95271 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GPR3 | P46089 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.48 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | IDE | P14735 | 1/20 | 0.44 |
| ▸ | MPI | P34949 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29755033 | 0.90 | KDM5A (0.51) | MAP3K11MAP3K9KDM4EALDH1A1LMNA | |
| SCHEMBL11768528 | 0.90 | KDM5A (0.51) | MAP3K11MAP3K9KDM4EALDH1A1LMNA | |
| SCHEMBL9781515 | 0.84 | CDK5 (0.64) | KDM4EALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL9768422 | 0.84 | CDK5 (0.50) | KDM4EALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL7252779 | 0.79 | MEN1 (0.55) | MEN1KMT2APARP1MAPTCA12 | |
| SCHEMBL10614432 | 0.77 | ALDH1A1 (0.45) | KDM4EALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL9781494 | 0.76 | CA12 (0.45) | KDM4EALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL10338976 | 0.76 | ALDH1A1 (0.41) | KDM4EALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL16049927 | 0.75 | MAP3K11 (0.51) | MAP3K11MAP3K9MEN1KMT2ACHEK1 | |
| SCHEMBL17465511 | 0.75 | MAP3K11 (0.51) | MAP3K11MAP3K9ALDH1A1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5073553-A | Treatment or prevention of osteoporosis | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1991-12-17 | — | — | US | disclosed |