Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10668886 | 0.91 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL10667568 | 0.89 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL10671413 | 0.86 | KDM4E (0.47) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL10668958 | 0.85 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL9781524 | 0.84 | KMT2A (0.42) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL10338976 | 0.81 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL9768420 | 0.79 | PARP1 (0.50) | HTTMAOA | |
| SCHEMBL10668875 | 0.78 | KCNA3 (0.44) | ALDH1A1LMNA | |
| SCHEMBL9781415 | 0.78 | KDM4E (0.55) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL9768425 | 0.78 | ADRB2 (0.46) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63295581-A | — | — | None | — | — | JP | disclosed |
| JP-63295582-A | — | — | None | — | — | JP | disclosed |
| JP-S63295581-A | BENZOFURO(3,2-C)QUINOLINE DERIVATIVE | KISSEI PHARMACEUT CO LTD | 1988-12-01 | — | — | JP | disclosed |
| JP-S63295582-A | REMEDY FOR OSTEOPOROSIS | KISSEI PHARMACEUT CO LTD | 1988-12-01 | — | — | JP | disclosed |
| EP-0293146-A1 | Benzofuro [3,2-c] quinoline compounds | Kissei Pharmaceutical Co. Ltd. (JP) | 1988-11-30 | — | — | EP | disclosed |