Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9768485 | 0.76 | MEN1 (0.38) | MEN1KMT2ATDP1 | |
| SCHEMBL7081506 | 0.73 | ALDH1A1 (0.71) | KDM4EALDH1A1HRH3MEN1KMT2A | |
| SCHEMBL4260570 | 0.72 | ALDH1A1 (0.97) | KDM4EALDH1A1HRH3MEN1KMT2A | |
| SCHEMBL9142598 | 0.71 | PPARA (0.43) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30605688 | 0.71 | ALDH1A1 (1.00) | KDM4EALDH1A1HRH3MEN1KMT2A | |
| SCHEMBL9137092 | 0.68 | S1PR1 (0.33) | — | |
| SCHEMBL418525 | 0.67 | ALDH1A1 (0.59) | KDM4EALDH1A1HRH3MEN1KMT2A | |
| SCHEMBL19663782 | 0.66 | CALM1 (0.67) | KDM4EALDH1A1HRH3MEN1KMT2A | |
| SCHEMBL30804399 | 0.66 | ALDH1A1 (0.47) | KDM4EALDH1A1HRH3MEN1KMT2A | |
| Bromide SCHEMBL9718079 | 0.65 | ATM (0.35) | KDM4ELMNAMAOBMAOAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5070099-A | THROMBOXANE ANTAGONISTS | E. R. SQUIBB & SONS, INC. (US) | 1991-12-03 | — | — | US | disclosed |
| US-5006542-A | Cardiovascular agents | E. R. SQUIBB & SONS, INC. (US) | 1991-04-09 | — | — | US | disclosed |