Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PREP | P48147 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 4/20 | 0.31 |
| ▸ | CA1 | P00915 | 4/20 | 0.31 |
| ▸ | CA9 | Q16790 | 4/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3843622 | 0.85 | PREP (0.44) | MEN1KMT2APREPTDP1CA12 | |
| SCHEMBL9813441 | 0.81 | MEN1 (0.38) | MEN1KMT2ATDP1 | |
| SCHEMBL9142598 | 0.80 | PPARA (0.43) | MEN1KMT2A | |
| SCHEMBL9137092 | 0.76 | S1PR1 (0.33) | ADRB3 | |
| SCHEMBL9652153 | 0.76 | TDP1 (0.43) | MEN1KMT2ATDP1 | |
| SCHEMBL4521924 | 0.76 | PREP (0.42) | MEN1KMT2APREPCA12CA1 | |
| SCHEMBL9768481 | 0.76 | KDM4E (0.54) | MEN1KMT2ATDP1 | |
| SCHEMBL6478757 | 0.75 | TDP1 (0.39) | MEN1KMT2ATDP1 | |
| Bromide SCHEMBL9718079 | 0.73 | ATM (0.35) | PREP | |
| SCHEMBL10633019 | 0.73 | MEN1 (0.33) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5070099-A | THROMBOXANE ANTAGONISTS | E. R. SQUIBB & SONS, INC. (US) | 1991-12-03 | — | — | US | disclosed |
| US-5006542-A | Cardiovascular agents | E. R. SQUIBB & SONS, INC. (US) | 1991-04-09 | — | — | US | disclosed |