Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4508541 | 0.89 | CALM1 (0.36) | KMT2AAOC3HRH3HTTSMN1; SMN2 | |
| SCHEMBL3085551 | 0.86 | TRPA1 (0.36) | ALDH1A1SLC6A4 | |
| SCHEMBL6179468 | 0.81 | CYP4F2 (0.45) | TDP1HRH3ALDH1A1CALM1 | |
| SCHEMBL4515768 | 0.79 | PPARA (0.46) | MEN1KMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9652153 | 0.79 | TDP1 (0.43) | TDP1MEN1KMT2AAOC3HRH3 | |
| SCHEMBL10438271 | 0.77 | HTT (0.34) | AOC3HRH3HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL3105485 | 0.77 | LTA4H (0.44) | HRH3SLC6A4 | |
| SCHEMBL22398087 | 0.77 | SLC6A4 (0.33) | HTTSMN1; SMN2ALDH1A1SLC6A4 | |
| SCHEMBL9768485 | 0.75 | MEN1 (0.38) | TDP1MEN1KMT2A | |
| SCHEMBL3581367 | 0.75 | POLB (0.52) | TDP1KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050240034-A1 | Artemisinin-based peroxide compounds as broad spectrum anti-infective agents | MISSISSIPPI, THE UNIVERSITY OF | 2005-10-27 | — | — | US | disclosed |
| WO-2003095444-A1 | ARTEMISININ-BASED PEROXIDE COMPOUNDS AS BROAD SPECTRUM ANTI-INFECTIVE AGENTS | UNIVERSITY OF MISSISSIPI (US) | 2003-11-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050240034-A1 | Artemisinin-based peroxide compounds as broad spectrum anti-infective agents | CASP10, HCCS, CASP9 | TDP1 4536/4885MEN1 4247/4885KMT2A 4321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.