Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 11/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28368180 | 0.83 | TBXAS1 (0.53) | TBXAS1PPARGPPARA | |
| SCHEMBL19463451 | 0.81 | TBXAS1 (0.50) | TBXAS1PPARGPPARAEPHX2 | |
| SCHEMBL19463449 | 0.81 | TBXAS1 (0.50) | TBXAS1PPARGPPARAEPHX2 | |
| SCHEMBL9520336 | 0.81 | TBXAS1 (0.53) | TBXAS1 | |
| SCHEMBL8461393 | 0.80 | TBXAS1 (0.49) | TBXAS1PPARGPPARAEPHX2 | |
| SCHEMBL10869186 | 0.79 | GRIK1 (0.53) | TBXAS1PPARGPPARAEPHX2 | |
| Hydrochloric Acid SCHEMBL28880680 | 0.79 | P4HTM (0.58) | TBXAS1PPARGPPARAEPHX2 | |
| SCHEMBL20213798 | 0.78 | TBXAS1 (0.49) | TBXAS1EPHX2 | |
| SCHEMBL30479399 | 0.78 | TBXAS1 (0.53) | TBXAS1PPARGPPARAEPHX2 | |
| SCHEMBL744044 | 0.77 | TBXAS1 (0.48) | TBXAS1PPARGPPARAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449764-A2 | A method of reducing serum uric acid and/or increasing renal uric acid clearance with thromboxane synthetase inhibitor and/or thromboxane receptor antagonist | CIBA-GEIGY AG (CH) | 1991-10-02 | — | — | EP | disclosed |
| US-5021448-A | Method of reducing serum uric acid and/or increasing renal uric acid clearance with thromboxane synthetase inhibitor inhibitor and/or thromboxane receptor antagonist | CIBA-GEIGY CORPORATION (US) | 1991-06-04 | — | — | US | disclosed |