Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9768774 | 0.95 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTMEN1LMNA | |
| SCHEMBL9768732 | 0.92 | ALDH1A1 (0.44) | ALDH1A1KDM4EMAPTMEN1LMNA | |
| Hydrochloric Acid SCHEMBL9768872 | 0.91 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTMEN1LMNA | |
| SCHEMBL9768706 | 0.88 | MAPT (0.44) | ALDH1A1KDM4EMAPTKMT2ASLC6A2 | |
| SCHEMBL9768711 | 0.87 | NPC1 (0.45) | ALDH1A1KDM4EMAPTMEN1LMNA | |
| SCHEMBL9768826 | 0.83 | MAPT (0.41) | ALDH1A1KDM4EMAPTMEN1LMNA | |
| SCHEMBL9768779 | 0.82 | NPC1 (0.45) | ALDH1A1KDM4EMAPTMEN1LMNA | |
| SCHEMBL9768718 | 0.79 | NR1I2 (0.46) | ALDH1A1MAPTMEN1LMNAKMT2A | |
| SCHEMBL9768790 | 0.79 | NPC1 (0.46) | ALDH1A1KDM4EMAPTMEN1LMNA | |
| Hydrochloric Acid SCHEMBL9768729 | 0.78 | MAPT (0.39) | ALDH1A1KDM4EMAPTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011833-A | Antidepressant | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE (IT) | 1991-04-30 | — | — | US | claimed |