Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.49 |
| ▸ | F7 | P08709 | 1/20 | 0.47 |
| ▸ | F3 | P13726 | 1/20 | 0.47 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.47 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.47 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29588286 | 0.82 | SLC18A3 (0.45) | ALDH1A1GAAAPPHCAR3HCAR2 | |
| SCHEMBL7447435 | 0.81 | SLC18A3 (0.58) | ALDH1A1GAAAPPHCAR3HCAR2 | |
| SCHEMBL2427999 | 0.81 | SLC18A3 (0.52) | ALDH1A1GAAAPPHCAR3HCAR2 | |
| SCHEMBL9768889 | 0.80 | GAA (0.44) | ALDH1A1GAAKDM4EMEN1KMT2A | |
| SCHEMBL9187512 | 0.79 | MCL1 (0.44) | MAPTMEN1KMT2ASLC18A3HTT | |
| SCHEMBL9665275 | 0.78 | SLC18A3 (0.56) | ALDH1A1GAAAPPHCAR3HCAR2 | |
| SCHEMBL8245353 | 0.78 | SLC18A3 (0.56) | ALDH1A1GAAAPPHCAR3HCAR2 | |
| SCHEMBL9769052 | 0.77 | F7 (0.40) | ALDH1A1GAAAPPHCAR3HCAR2 | |
| SCHEMBL5046019 | 0.77 | SLC18A3 (0.54) | ALDH1A1GAAAPPHCAR3HCAR2 | |
| SCHEMBL18239397 | 0.77 | CHRNB2 (0.57) | ALDH1A1GAAAPPHCAR3HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023334-A | Anthelmintic pyridinyl acylhydrazones | THE UPJOHN COMPANY (US) | 1991-06-11 | — | — | US | disclosed |
| US-5011932-A | Anthelmintic pyridinyl acylhydrazones derivatives | UPJOHN COMPANY (US) | 1991-04-30 | — | — | US | disclosed |
| EP-0214158-A1 | ANTHELMINTIC PYRIDINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1987-03-18 | — | — | EP | disclosed |
| WO-1986004582-A1 | ANTHELMINTIC PYRIDINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1986-08-14 | — | — | WO | disclosed |
| EP-0080847-A2 | Improvements in or relating to the synthesis of dioxane analgesics | ELI LILLY AND COMPANY (US) | 1983-06-08 | — | — | EP | disclosed |
| US-4376860-A | Pyridyl ketone | ELI LILLY AND COMPANY (US) | 1983-03-15 | — | — | US | disclosed |