SCHEMBL9768856

SCHEMBL9768856

COc1ccc(SCCOc2ccccc2C)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 8/20 0.51
GAA P10253 3/20 0.51
AR P10275 1/20 0.49
NPSR1 Q6W5P4 2/20 0.49
MAPK1 P28482 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
NPC1 O15118 1/20 0.49
TP53 P04637 1/20 0.49
RAB9A P51151 1/20 0.49
HPGD P15428 2/20 0.48
LMNA P02545 2/20 0.48
KMT2A Q03164 1/20 0.48
TDP1 Q9NUW8 4/20 0.47
MAPT P10636 4/20 0.46
PKM P14618 1/20 0.46
HTT P42858 1/20 0.45
ATM Q13315 2/20 0.44
DRD2 P14416 1/20 0.44
DRD4 P21917 1/20 0.44
DRD3 P35462 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20005776 0.85 MAPT (0.55) L3MBTL1GAAARNPSR1SMN1; SMN2
SCHEMBL12301165 0.85 L3MBTL1 (0.57) L3MBTL1GAAARNPSR1MAPK1
SCHEMBL5824932 0.83 KMT2A (0.52) L3MBTL1GAAARNPSR1HPGD
SCHEMBL386935 0.82 L3MBTL1 (0.65) L3MBTL1NPSR1SMN1; SMN2NPC1TP53
SCHEMBL9770356 0.80 NPC1 (0.63) L3MBTL1GAANPSR1MAPK1SMN1; SMN2
SCHEMBL10598373 0.78 RAB9A (0.65) L3MBTL1GAANPSR1MAPK1SMN1; SMN2
SCHEMBL12301152 0.78 L3MBTL1 (0.54) L3MBTL1MAPK1SMN1; SMN2HPGDLMNA
SCHEMBL23527296 0.77 AR (0.52) L3MBTL1GAAARNPSR1SMN1; SMN2
SCHEMBL9768860 0.77 NPC1 (0.58) L3MBTL1GAANPSR1MAPK1SMN1; SMN2
SCHEMBL5825561 0.77 FGFR2 (0.55)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4994431-A Containing colorless dye precursor, color developer and 1-alkoxy-phenoxy-2-aryloxypropane sensitizer; preservation stability, high sensitivity FUJI PHOTO FILM CO., LTD. (JP) 1991-02-19 US disclosed