Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.63 |
| ▸ | RAB9A | P51151 | 5/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 2/20 | 0.56 |
| ▸ | DRD4 | P21917 | 2/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10598373 | 0.95 | RAB9A (0.65) | NPC1RAB9ASMN1; SMN2MAPK1NPSR1 | |
| SCHEMBL10345794 | 0.92 | SMN1; SMN2 (0.58) | NPC1RAB9ASMN1; SMN2MAPK1NPSR1 | |
| SCHEMBL10345453 | 0.89 | MAPK1 (0.55) | NPC1RAB9ASMN1; SMN2MAPK1NPSR1 | |
| SCHEMBL9768860 | 0.86 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2MAPK1NPSR1 | |
| SCHEMBL10345795 | 0.86 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2MAPK1NPSR1 | |
| SCHEMBL10345911 | 0.86 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2MAPK1NPSR1 | |
| SCHEMBL10346037 | 0.86 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2MAPK1NPSR1 | |
| SCHEMBL9808023 | 0.85 | ALDH1A1 (0.61) | NPC1RAB9ASMN1; SMN2MAPK1TP53 | |
| SCHEMBL5824912 | 0.84 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2MAPK1NPSR1 | |
| SCHEMBL9808032 | 0.84 | DRD2 (0.69) | NPC1RAB9ASMN1; SMN2TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985393-A | Bis/hydroxyphenylthio/ Compounds | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| US-4981836-A | Recording material | FUJI PHOTO FILM CO., LTD. (JP) | 1991-01-01 | — | — | US | disclosed |
| EP-0373561-A2 | Heat sensitive recording material | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1990-06-20 | — | — | EP | disclosed |
| US-4835133-A | Recording material | FUJI PHOTO FILM CO., LTD. (JP) | 1989-05-30 | — | — | US | disclosed |