Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9768780 | 0.89 | CYP2D6 (0.47) | ALDH1A1TP53KDM4ELMNATSHR | |
| SCHEMBL9768990 | 0.88 | ALDH1A1 (0.45) | ALDH1A1TSHRHTTDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL9768700 | 0.85 | HSD17B10 (0.42) | ALDH1A1TP53KDM4ELMNADRD2 | |
| SCHEMBL9768722 | 0.79 | NPC1 (0.44) | ALDH1A1TP53LMNADRD3MEN1 | |
| Hydrochloric Acid SCHEMBL9768729 | 0.76 | MAPT (0.39) | ALDH1A1TP53KDM4ELMNAHTT | |
| Hydrochloric Acid SCHEMBL9768816 | 0.73 | MAPT (0.35) | ALDH1A1TP53LMNADRD3MAPT | |
| SCHEMBL9768740 | 0.72 | CYP2D6 (0.53) | ALDH1A1TP53KDM4ELMNATSHR | |
| SCHEMBL9768831 | 0.70 | ALDH1A1 (0.56) | ALDH1A1TP53KDM4EGAAHTT | |
| Hydrochloric Acid SCHEMBL9768751 | 0.69 | ALDH1A1 (0.44) | ALDH1A1TP53KDM4ELMNATSHR | |
| SCHEMBL9768745 | 0.67 | TP53 (0.62) | ALDH1A1TP53KDM4ETSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011833-A | Antidepressant | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE (IT) | 1991-04-30 | — | — | US | disclosed |