Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 5/20 | 0.40 |
| ▸ | HTR7 | P34969 | 4/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9768780 | 0.91 | CYP2D6 (0.47) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL9768899 | 0.88 | ALDH1A1 (0.46) | ALDH1A1MAPTMEN1KMT2AHTT | |
| Hydrochloric Acid SCHEMBL9768700 | 0.87 | HSD17B10 (0.42) | ALDH1A1MAPTMEN1KMT2ADRD2 | |
| SCHEMBL9768722 | 0.81 | NPC1 (0.44) | ALDH1A1MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9768729 | 0.78 | MAPT (0.39) | ALDH1A1MAPTMEN1KMT2AHTT | |
| Hydrochloric Acid SCHEMBL9768816 | 0.75 | MAPT (0.35) | ALDH1A1MAPTCYP3A4CYP2D6 | |
| SCHEMBL9768740 | 0.74 | CYP2D6 (0.53) | ALDH1A1MAPTKMT2AHTTCYP3A4 | |
| SCHEMBL9768831 | 0.72 | ALDH1A1 (0.56) | ALDH1A1MAPTMEN1KMT2AHTT | |
| Hydrochloric Acid SCHEMBL9768751 | 0.71 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL9768745 | 0.69 | TP53 (0.62) | ALDH1A1MAPTMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011833-A | Antidepressant | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE (IT) | 1991-04-30 | — | — | US | disclosed |