Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19258005 | 0.86 | SIGMAR1 (0.46) | LTA4HSIGMAR1TAAR1SLC18A2CYP2D6 | |
| SCHEMBL19258136 | 0.86 | SIGMAR1 (0.46) | LTA4HSIGMAR1TAAR1SLC18A2CYP2D6 | |
| SCHEMBL23116559 | 0.80 | CTRB1 (0.49) | CYP3A4CYP2D6TSHRCYP2C19OPRK1 | |
| SCHEMBL13136121 | 0.80 | CTRB1 (0.49) | CYP3A4CYP2D6TSHRCYP2C19OPRK1 | |
| SCHEMBL6009261 | 0.80 | SIGMAR1 (0.51) | SIGMAR1TSHR | |
| SCHEMBL11991363 | 0.80 | EPHX1 (0.65) | LTA4HSIGMAR1TAAR1SLC6A3CYP3A4 | |
| SCHEMBL15624910 | 0.78 | EPHX1 (0.63) | SIGMAR1TAAR1SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL11991372 | 0.78 | EPHX1 (0.63) | SIGMAR1TAAR1SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL13115951 | 0.78 | CYP3A4 (0.51) | LTA4HCYP3A4OPRK1 | |
| SCHEMBL13405239 | 0.78 | TAAR1 (0.41) | SIGMAR1TAAR1SLC18A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030649-A | Analgesics | DR. LO. ZAMBELLETTI S.P.A. (IT) | 1991-07-09 | — | — | US | disclosed |
| EP-0261842-B1 | N1-ACYLATED-(1-(PHENYL OR BENZYL))-1,2-ETHYLENE DIAMINES | Dr. Lo. Zambeletti S.p.A. (IT) | 1990-11-22 | — | — | EP | disclosed |
| EP-0261842-A1 | N1-acylated-(1-(phenyl or benzyl))-1,2-ethylene diamines | Dr. Lo. Zambeletti S.p.A. (IT) | 1988-03-30 | — | — | EP | disclosed |