Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | EBP | Q15125 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5759253 | 0.82 | DPP7 (0.47) | SIGMAR1HRH3EBPALDH1A1LMNA | |
| Fenpropidin SCHEMBL8445539 | 0.81 | SIGMAR1 (0.62) | SIGMAR1HRH3EBPKDM4EALDH1A1 | |
| Fenpropidin SCHEMBL21278 | 0.81 | SIGMAR1 (0.62) | SIGMAR1HRH3EBPKDM4EALDH1A1 | |
| Fenpropidin SCHEMBL8148240 | 0.81 | SIGMAR1 (0.62) | SIGMAR1HRH3EBPKDM4EALDH1A1 | |
| Fenpropidin SCHEMBL9020970 | 0.81 | SIGMAR1 (0.62) | SIGMAR1HRH3EBPKDM4EALDH1A1 | |
| SCHEMBL9769074 | 0.80 | LTA4H (0.49) | SIGMAR1TSHR | |
| SCHEMBL5758272 | 0.79 | CTRB1 (0.48) | SIGMAR1ALDH1A1TSHRCYP2C9LMNA | |
| SCHEMBL9370705 | 0.79 | SIGMAR1 (0.63) | SIGMAR1HRH3EBPKDM4EALDH1A1 | |
| SCHEMBL11459415 | 0.78 | SIGMAR1 (0.52) | SIGMAR1HRH3EBPKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL6007530 | 0.78 | SIGMAR1 (0.52) | SIGMAR1HRH3EBPKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078537-B2 | Phenylalkyl diamine and amide analogs | SK CORPORATION (KR) | 2006-07-18 | — | — | US | disclosed |
| US-20030105079-A1 | Novel phenylalkyl diamine and amide analogs | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2003-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105079-A1 | Novel phenylalkyl diamine and amide analogs | SIGMAR1, TAAR1, OPRL1 | SIGMAR1 1/4885HRH3 163/4885EBP 1434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.