Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9587060 | 0.83 | MAPT (0.37) | NPC1RAB9AGSK3BMAPTNPSR1 | |
| SCHEMBL27630654 | 0.77 | KEAP1 (0.45) | GSK3BMAPTDAO | |
| SCHEMBL28221583 | 0.76 | DAO (0.39) | DAO | |
| SCHEMBL13841376 | 0.76 | — | — | |
| SCHEMBL12427 | 0.75 | — | — | |
| SCHEMBL12449621 | 0.74 | SLC6A2 (0.33) | — | |
| SCHEMBL6384656 | 0.70 | — | — | |
| SCHEMBL12670697 | 0.70 | — | — | |
| SCHEMBL7600298 | 0.67 | LTB4R (0.40) | DAO | |
| SCHEMBL27429962 | 0.67 | PNMT (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992534-A | Anticarcinogenic agents with better water solubility, low toxicity, absorption and stability | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-12 | — | — | US | disclosed |
| CN-1031536-A | 2 '-'-Deoxy-5-fluorouridine derivatives and its production and application | OTSUKA PHARMA CO LTD (JP) | 1989-03-08 | — | — | CN | disclosed |
| EP-0303269-A2 | 2'-Deoxy-5-fluorouridine derivatives, process for preparing the same and the use thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-02-15 | — | — | EP | disclosed |