Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45854 | 0.82 | — | — | |
| SCHEMBL9880895 | 0.77 | HPGD (0.50) | ALDH1A1HPGDRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL6844117 | 0.76 | PRMT6 (0.50) | ALDH1A1HPGDRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL4096475 | 0.76 | ALDH1A1 (0.43) | ALDH1A1HPGDRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL2969315 | 0.75 | — | — | |
| SCHEMBL10175255 | 0.75 | ALDH1A1 (0.36) | ALDH1A1HPGDRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL27288252 | 0.74 | ALDH1A1 (0.44) | ALDH1A1HPGDRAB9ASMN1; SMN2TSHR | |
| SCHEMBL9880894 | 0.73 | ACACA (0.44) | ALDH1A1HPGDRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL21547852 | 0.73 | HPGD (0.40) | ALDH1A1HPGDRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL2037052 | 0.71 | HPGD (0.38) | ALDH1A1HPGDRAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992534-A | Anticarcinogenic agents with better water solubility, low toxicity, absorption and stability | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-12 | — | — | US | disclosed |
| CN-1031536-A | 2 '-'-Deoxy-5-fluorouridine derivatives and its production and application | OTSUKA PHARMA CO LTD (JP) | 1989-03-08 | — | — | CN | disclosed |
| EP-0303269-A2 | 2'-Deoxy-5-fluorouridine derivatives, process for preparing the same and the use thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-02-15 | — | — | EP | disclosed |