Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | PRCP | P42785 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2723323 | 0.94 | LMNA (0.44) | GBA2DPP4LMNAPOLBSMN1; SMN2 | |
| SCHEMBL32681452 | 0.94 | LMNA (0.44) | GBA2DPP4LMNAPOLBSMN1; SMN2 | |
| SCHEMBL9275749 | 0.90 | SMN1; SMN2 (0.43) | GBA2LMNAPOLBSMN1; SMN2MAPT | |
| SCHEMBL12133179 | 0.83 | RAB9A (0.43) | POLBL3MBTL1 | |
| SCHEMBL13532420 | 0.83 | RAB9A (0.43) | POLBL3MBTL1 | |
| SCHEMBL27919865 | 0.83 | HPGD (0.42) | GBA2DPP4LMNAPOLBSMN1; SMN2 | |
| SCHEMBL6207726 | 0.81 | LMNA (0.40) | GBA2DPP4LMNAPOLBSMN1; SMN2 | |
| SCHEMBL7771251 | 0.80 | RAB9A (0.59) | GBA2LMNASMN1; SMN2L3MBTL1PRCP | |
| SCHEMBL7771246 | 0.80 | RAB9A (0.59) | GBA2LMNASMN1; SMN2L3MBTL1PRCP | |
| SCHEMBL9769179 | 0.79 | GBA2 (0.47) | GBA2NAAADPP4LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3659609-A1 | THERAPEUTIC AGENT FOR FIBROSIS | Kyorin Pharmaceutical Co., Ltd. (JP) | 2020-06-03 | — | — | EP | disclosed |
| US-4992534-A | Anticarcinogenic agents with better water solubility, low toxicity, absorption and stability | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-12 | — | — | US | disclosed |
| EP-0303269-A2 | 2'-Deoxy-5-fluorouridine derivatives, process for preparing the same and the use thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-02-15 | — | — | EP | disclosed |