Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 4/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7172715 | 0.94 | LMNA (0.43) | GBA2DPP4LMNAPOLBSMN1; SMN2 | |
| SCHEMBL3922358 | 0.82 | LMNA (0.42) | GBA2DPP4LMNAPOLBSMN1; SMN2 | |
| SCHEMBL21243398 | 0.82 | DPP4 (0.56) | DPP4 | |
| SCHEMBL9769183 | 0.79 | GBA2 (0.48) | GBA2DPP4NAAALMNAPOLB | |
| SCHEMBL7771251 | 0.79 | RAB9A (0.59) | GBA2LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL7771246 | 0.79 | RAB9A (0.59) | GBA2LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL16124534 | 0.77 | RAB9A (0.61) | GBA2LMNASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL7294053 | 0.77 | FKBP1A (0.50) | DPP4SMN1; SMN2 | |
| SCHEMBL10612338 | 0.75 | GBA2 (0.53) | GBA2NAAALMNAPOLBSMN1; SMN2 | |
| SCHEMBL2731646 | 0.75 | POLB (0.46) | GBA2DPP4LMNAPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992534-A | Anticarcinogenic agents with better water solubility, low toxicity, absorption and stability | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-12 | — | — | US | disclosed |
| CN-1031536-A | 2 '-'-Deoxy-5-fluorouridine derivatives and its production and application | OTSUKA PHARMA CO LTD (JP) | 1989-03-08 | — | — | CN | disclosed |
| EP-0303269-A2 | 2'-Deoxy-5-fluorouridine derivatives, process for preparing the same and the use thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-02-15 | — | — | EP | disclosed |