Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9769293 | 0.78 | TSHR (0.34) | USP2KDM4EALDH1A1HPGD | |
| SCHEMBL6901097 | 0.73 | ALDH1A1 (0.37) | USP2ALDH1A1 | |
| SCHEMBL20645742 | 0.71 | USP2 (0.39) | USP2 | |
| SCHEMBL19274401 | 0.68 | ALOX15 (0.32) | USP2ALDH1A1 | |
| SCHEMBL6903369 | 0.68 | ERCC5 (0.34) | USP2 | |
| SCHEMBL15090211 | 0.64 | LTB4R (0.35) | USP2 | |
| SCHEMBL18420119 | 0.63 | HPGD (0.46) | USP2KDM4EALDH1A1HPGD | |
| SCHEMBL9243180 | 0.62 | KMT2A (0.34) | ALDH1A1HPGD | |
| Formaldehyde SCHEMBL27723347 | 0.60 | GRIN2D (0.46) | — | |
| SCHEMBL1521934 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992534-A | Anticarcinogenic agents with better water solubility, low toxicity, absorption and stability | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-12 | — | — | US | disclosed |
| CN-1031536-A | 2 '-'-Deoxy-5-fluorouridine derivatives and its production and application | OTSUKA PHARMA CO LTD (JP) | 1989-03-08 | — | — | CN | disclosed |
| EP-0303269-A2 | 2'-Deoxy-5-fluorouridine derivatives, process for preparing the same and the use thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-02-15 | — | — | EP | disclosed |