Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14672809 | 0.66 | KMT2A (0.33) | TSHR | |
| SCHEMBL3205487 | 0.66 | AHR (0.41) | — | |
| SCHEMBL3209050 | 0.66 | CYP11B2 (0.37) | TSHR | |
| SCHEMBL7915878 | 0.62 | ALDH1A1 (0.33) | TSHR | |
| SCHEMBL18078709 | 0.62 | EGLN2 (0.53) | TSHR | |
| SCHEMBL9769233 | 0.60 | KMT2A (0.33) | — | |
| SCHEMBL1187776 | 0.59 | — | — | |
| SCHEMBL18078708 | 0.58 | ALDH1A1 (0.42) | TSHR | |
| SCHEMBL12333928 | 0.53 | TSHR (0.37) | TSHR | |
| SCHEMBL1666667 | 0.53 | TSHR (0.37) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019578-A | β-adrenergic agonists | MERCK & CO., INC. (US) | 1991-05-28 | — | — | US | disclosed |
| EP-0318092-A2 | Novel beta-adrenergic agonists | MERCK & CO. INC. (US) | 1989-05-31 | — | — | EP | disclosed |