SCHEMBL9769481

SCHEMBL9769481

CNc1ccc(O)c(NC)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.48
APP P05067 6/20 0.43
ALDH1A1 P00352 2/20 0.40
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.40
THRB P10828 1/20 0.40
HPGD P15428 1/20 0.40
ALOX15 P16050 1/20 0.40
CASP1 P29466 1/20 0.40
RECQL P46063 1/20 0.40
HIF1A Q16665 1/20 0.40
HSD17B10 Q99714 1/20 0.40
GAA P10253 1/20 0.38
GFER P55789 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38
ESR1 P03372 1/20 0.36
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
NR1H4 Q96RI1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2195425 0.81 IDO1 (0.48) IDO1APPALDH1A1TP53CYP3A4
SCHEMBL84733 0.80 ARG1 (0.48) IDO1APPALDH1A1TP53CYP3A4
SCHEMBL23432543 0.78 IDO1 (0.53) IDO1APPALDH1A1TP53ALOX15
SCHEMBL23226873 0.78 IDO1 (0.35) IDO1APPALDH1A1TP53CYP3A4
SCHEMBL23226555 0.78 ADRA2A (0.58) ALDH1A1TP53CYP3A4THRBHPGD
SCHEMBL23226775 0.78 GAA (0.49) IDO1ALDH1A1TP53CYP3A4THRB
SCHEMBL7565978 0.78 CXCR2 (0.49) IDO1ALDH1A1CYP3A4HPGDALOX15
SCHEMBL2620520 0.78 HDAC1 (0.48) IDO1APPGFERAPOBEC3GMAPT
SCHEMBL5795933 0.78 IDO1 (0.45) IDO1APPALDH1A1TP53CYP3A4
SCHEMBL30963343 0.78 IDO1 (0.45) IDO1APPALDH1A1TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104262678-A Additive for polymer JIANG KAIWEN 2015-01-07 CN disclosed
US-5037726-A Imagewise exposure of photographic light sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1991-08-06 US disclosed
US-4968596-A DEVELOPMENT IN PRESENCE OF NUCLEATION AGENT FUJI PHOTO FILM CO. LTD. (JP) 1990-11-06 US disclosed
EP-0315890-A1 Method for forming a direct positive image FUJI PHOTO FILM CO., LTD. (JP) 1989-05-17 EP disclosed
US-4179294-A POLYMER MORDANT, ACIDIC PYRAZOLONE-CONTAINING OXONOL DYE, READILY DECOLORIZED BY IMMOBILIZATION FUJI PHOTO FILM CO., LTD. (JP) 1979-12-18 US disclosed