SCHEMBL7565978

SCHEMBL7565978

CNc1ccc(O)c(Nc2cc(Cl)ccc2O)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CXCR2 P25025 1/20 0.49
KCNMA1 Q12791 8/20 0.44
POLB P06746 1/20 0.44
MAPKAPK2 P49137 2/20 0.43
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
MAPT P10636 2/20 0.42
HTT P42858 2/20 0.42
MAPK1 P28482 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
HPGD P15428 3/20 0.41
TNNI3K Q59H18 1/20 0.41
SLC22A1 O15245 1/20 0.41
USP2 O75604 1/20 0.41
LMNA P02545 1/20 0.41
HSP90AA1 P07900 1/20 0.41
CYP3A4 P08684 1/20 0.41
HSPD1 P10809 1/20 0.41
HSPA5 P11021 1/20 0.41
IDO1 P14902 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11014515 0.81 KCNMA1 (0.52) CXCR2KCNMA1POLBMEN1KMT2A
SCHEMBL30035007 0.81 KCNMA1 (0.52) CXCR2KCNMA1POLBMEN1KMT2A
SCHEMBL9769481 0.78 IDO1 (0.48) MAPTHPGDCYP3A4IDO1ALOX15
SCHEMBL11091688 0.76 CXCR2 (0.57) CXCR2KCNMA1POLBMAPKAPK2MEN1
SCHEMBL23226618 0.73 HSD17B2 (0.61) MEN1KMT2AMAPTHTTTNNI3K
SCHEMBL7301879 0.73 ALDH1A1 (0.59) CXCR2KCNMA1POLBMAPKAPK2MAPK1
SCHEMBL27968138 0.73 CXCR2 (0.54) CXCR2KCNMA1POLBMAPKAPK2MAPT
SCHEMBL10001895 0.72 HSD17B10 (0.50) MAPTHPGDLMNAHSP90AA1CYP3A4
SCHEMBL27418785 0.71 P2RX1 (0.57) CXCR2KCNMA1MEN1KMT2AMAPT
SCHEMBL84733 0.69 ARG1 (0.48) MEN1KMT2AMAPTMAPK1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1022015-B1 PROCESS FOR PREPARING A HAIR DYEING COMPOSITION GOLDWELL GMBH (DE) 2002-09-04 EP disclosed
EP-0998897-B1 Method for manufacturing stable aqueous hair dye emulsions GOLDWELL AG (DE) 2001-02-28 EP disclosed
EP-0950395-B1 Method for manufacturing stable aqueous hair dye emulsions GOLDWELL GMBH (DE) 2001-02-21 EP disclosed
EP-1022015-A2 PROCESS FOR PREPARING A HAIR DYEING COMPOSITION GOLDWELL GmbH (DE) 2000-07-26 EP disclosed
EP-0998897-A1 Method for manufacturing stable aqueous hair dye emulsions GOLDWELL AKTIENGESELLSCHAFT (DE) 2000-05-10 EP disclosed
EP-0950395-A1 Method for manufacturing stable aqueous hair dye emulsions GOLDWELL GmbH (DE) 1999-10-20 EP disclosed