SCHEMBL9769554

SCHEMBL9769554

O=C(Br)c1ccc(-c2ccc(C(=O)Br)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.46
NPC1 O15118 1/20 0.46
CTDSP1 Q9GZU7 1/20 0.46
PTPN1 P18031 4/20 0.44
GSK3B P49841 1/20 0.44
MAPT P10636 2/20 0.44
BCL2L1 Q07817 1/20 0.44
BAD Q92934 1/20 0.44
HSD17B1 P14061 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
HDAC1 Q13547 3/20 0.43
HDAC6 Q9UBN7 2/20 0.43
MEN1 O00255 1/20 0.41
LMNA P02545 1/20 0.41
KMT2A Q03164 1/20 0.41
RXRA P19793 1/20 0.40
RXRB P28702 1/20 0.40
SRD5A2 P31213 1/20 0.40
TP53 P04637 1/20 0.40
TSHR P16473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL688186 0.90 TP53 (0.47) MAPTHDAC6LMNAKMT2ASRD5A2
SCHEMBL15395891 0.83 GSK3B (0.70) RAB9APTPN1GSK3BMAPTSMN1; SMN2
SCHEMBL9173480 0.81 SRD5A2 (0.55) RAB9ANPC1MAPTMEN1LMNA
SCHEMBL10391056 0.79 TSHR (0.71) SMN1; SMN2SRD5A2TP53TSHR
SCHEMBL1991482 0.79 CES2 (0.65) RAB9ACTDSP1GSK3BMAPTSMN1; SMN2
SCHEMBL7153626 0.79 MAPT (0.60) RAB9ANPC1PTPN1MAPTHSD17B1
SCHEMBL1991237 0.77 TPMT (0.59) PTPN1GSK3BRXRARXRBTP53
SCHEMBL1996245 0.77 CES2 (0.62) CTDSP1GSK3BMAPTLMNASRD5A2
SCHEMBL1563535 0.77 CES2 (0.62) RAB9ANPC1PTPN1BCL2L1BAD
SCHEMBL1290706 0.77 KMT2A (0.61) SMN1; SMN2HDAC1HDAC6LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3512905-B1 METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) BASF SE (DE) 2022-08-24 EP claimed
CN-111836849-B Process for producing fibers, films and moldings of polybenzazole polymer (P) 巴斯夫欧洲公司 2023-04-07 CN disclosed
CN-110177824-B Method for producing polyamideimide film SKC株式会社 2022-09-09 CN disclosed
EP-3512905-B1 METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) BASF SE (DE) 2022-08-24 EP disclosed
US-20200407508-A1 METHOD FOR PRODUCING FIBERS, FILMS AND MOLDINGS OF A POLYBENZAZOLE POLYMER (P) BASF SE (DE) 2020-12-31 US disclosed
CN-111836849-A Process for producing fibers, films and moldings of polybenzazole polymer (P) 巴斯夫欧洲公司 2020-10-27 CN disclosed
US-20200048418-A1 A PROCESS FOR PREPARING A POLYARYLENESULFONE/POLYESTER BLOCK COPOLYMER (P) BASF SE (DE) 2020-02-13 US disclosed
EP-3601408-A1 A PROCESS FOR PREPARING A POLYARYLENESULFONE/POLYESTER BLOCK COPOLYMER (P) Virginia Tech Intellectual Properties, Inc. (US) 2020-02-05 EP disclosed
WO-2018183280-A1 A PROCESS FOR PREPARING A POLYARYLENESULFONE/POLYESTER BLOCK COPOLYMER (P) VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY (US) 2018-10-04 WO disclosed
EP-3381965-A1 A PROCESS FOR PREPARING A POLYARYLENESULFONE/POLYESTER BLOCK COPOLYMER (P) BASF SE (DE) 2018-10-03 EP disclosed
US-9321017-B2 Gas-separation membrane NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTE (JP) 2016-04-26 US disclosed
US-20150033945-A1 GAS-SEPARATION MEMBRANE NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTE (JP) 2015-02-05 US disclosed
US-4992526-A Preparation of polyarylate polymers of hydroxyaryl-substituted 1,6-diaza [4.] spirodilactams SHELL OIL COMPANY (US) 1991-02-12 US disclosed
US-4977235-A From aromatic dicarboxylic acids and hydroxyaryl-substituted 1,6-diaza(4.4)spirodilactams; molding materials; high glass transition temperatures SHELL OIL COMPANY (US) 1990-12-11 US disclosed
US-4910285-A Polyarylate polymers SHELL OIL COMPANY (US) 1990-03-20 US disclosed
US-4278786-A BIS/P-AMINOPHENOL ETHER OF A BISPHENOL HITACHI, LTD. (JP) 1981-07-14 US disclosed